Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene39855618396649823971796339736060397792673973485639738431397234733972598939728238397294903973870939739948397435813974369039760300
Basic Information
VIS ID
TVIS44018871
Fusion event
HTLV-1-THUMPD2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
39987440/39760300 (Hg38)
End
39987440/39760300 (Hg38)
Orient
+
Location type
Intronic
Target gene
THUMPD2
Nearest miRNA
hsa-mir-1301/Upstream/4288814; hsa-mir-10b/Downstream/7617375;
Nearest TSS
ENST00000437798/Upstream/15646; ENST00000627210/Downstream/5912;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/93789, chr2-CpG: 53/Downstream/18650
Upstream sequence
GGTCTCACTGTAGAGAGGAGAAGAGAAAAAAGTACTCTAAAGGTCTCATCTTATGACAGGGAAGAGGGGGAAGTTGGGGAAAATTGGAGTGCCTTGGTAA
Downstream sequence
AAACGGTGTGTCTTGGCAGAGGGAGTAGTTGATGTTCTGTTTTAAATTAAGAGTAGAGTCATATATATTTAGTTAAGAGAGCTGGGAAAAGGACTGTAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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