Basic Information
VIS ID
TVIS44018888
Fusion event
HTLV-1-ACYP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.2
Reference genome
GRCh37/hg19
Start
54318127/54090990 (Hg38)
End
54318127/54090990 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2D ; FRA2H
Target gene
ACYP2
Nearest miRNA
hsa-mir-1301/Upstream/241785; hsa-mir-10b/Downstream/1891977;
Nearest TSS
ENST00000437798/Upstream/8436; ENST00000406041/Downstream/24413;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/119637, chr2-CpG: 47/Downstream/24507
Nearby gene
ACYP2(+24283) ;
Upstream sequence
TCCATGTATTTGGATGATTTTACCATCTACATGTTGGTGCTTTGAGGGTAGGAATTCTACACTAGACATCTTTGTTTCCATGATGTTGCCTTGGACACAA
Downstream sequence
TGAACGCTGACATAATTGTTGATTGATTTAAAATACATTTTTCTATTTTTAAAATAGGCAGAGAAGAAACTCTACTAATGTTTCTCAACACCTACAAGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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