Basic Information
VIS ID
TVIS44018893
Fusion event
HTLV-1-LOC105377632 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
57531904/57304769 (Hg38)
End
57531904/57304769 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105377632
Nearest miRNA
hsa-mir-1301/Upstream/1303974; hsa-mir-10b/Downstream/3082593;
Nearest TSS
ENST00000437798/Upstream/1118999; ENST00000463222/Downstream/602882;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1119365, chr2-CpG: 81/Downstream/741738
Nearby gene
VRK2(+602882) ;
Upstream sequence
GAAATTGGAATGTCCTTTTTGAATTAAACACTTGCTTTATTACCTTTTACTGTAAAACTTAATTTGTTATTTAGTCACAGCCATTATGAAATATAATATG
Downstream sequence
TGCAATTATCAAATATTCTTATAAGAGTACCAGACAGTGAAGGGGACCAAACAATAACTTGCTGAATGTTTCAATAAACGTTAAAGAAAGTATGCAATTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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