Basic Information
VIS ID
TVIS44018895
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
60096263/59869128 (Hg38)
End
60096263/59869128 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/3868333; hsa-mir-10b/Downstream/518234;
Nearest TSS
ENST00000437798/Upstream/135732; ENST00000444873/Downstream/231072;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1440151, chr2-CpG: 103/Downstream/591559
Nearby gene
MIR4432HG(No orient, 490088)
Upstream sequence
CTCGGTGGTAAATTTGTCTTATGTGTCGATTTCAGCAGGCTACTCTCTGCAGATGTACACATGTGTGCTGATTTCCTGCCCTCCAAAATTATTTTTCTGG
Downstream sequence
TTGTGGACATATGGTGAGCAATAGTTGGAATAGTTATTCAGGGTGCAGGCTCCCCTCTGGGATCTGTGGGATAAATCTTGCTCCTTCTGTCAAGTCAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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