Basic Information
VIS ID
TVIS44018902
Fusion event
HTLV-1-LINC00487 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.2
Reference genome
GRCh37/hg19
Start
6903307/6763176 (Hg38)
End
6903307/6763176 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00487
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-7158/Upstream/112737; hsa-mir-10b/Downstream/3429438;
Nearest TSS
ENST00000437798/Upstream/31854; ENST00000474872/Downstream/7135;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/267148, chr2-CpG: 137/Downstream/101856
Upstream sequence
TTTTAAATTTGGCATAGCAATACTCAGCAGTAGACACTCAGTGCTTTTGGAAAAAAAAAAAAAAAAACTAAACTAACAAAAGGGAAGTAAATTCTTCAGT
Downstream sequence
TTACTCTGCTCCTGAGCTGAGGTTTGACTCCAATGTGGTGGCGGCTACAATAATGGAGTGGTGAGGTGCACCTCTCACCCTCCTCCAGTTTATAGTTCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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