VISDB Viral Integration Site DataBase

VIS ID

TVIS44018906

Fusion event

HTLV-1-TET3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

p13.1

Reference genome

Start

End

74235009/74007882 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA2S ; FRA2E

Target gene

miRNAs that regulate target gene

hsa-mir-548b-3p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-410-5p ; hsa-mir-494-5p ; hsa-mir-584-5p ; hsa-mir-758-5p ; hsa-mir-1297 ; hsa-mir-1306-5p ; hsa-mir-323b-5p ; hsa-mir-4465 ; hsa-mir-5697 ; hsa-mir-6074 ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-149-3p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-2110 ; hsa-mir-3148 ; hsa-mir-4271 ; hsa-mir-4667-5p ; hsa-mir-4700-5p ; hsa-mir-4725-3p ; hsa-mir-4728-5p ; hsa-mir-6785-5p ; hsa-mir-6780b-5p ; hsa-mir-6883-5p ; hsa-mir-8089 ; hsa-mir-142-3p ; hsa-mir-3177-3p ; hsa-mir-5186 ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-3613-3p ; hsa-mir-141-3p ; hsa-mir-374a-5p ; hsa-mir-1249-5p ; hsa-mir-6770-5p ; hsa-mir-6797-5p ; hsa-mir-3136-5p ; hsa-mir-4439 ; hsa-mir-6857-3p ; hsa-mir-4267 ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-508-5p ; hsa-mir-766-3p ; hsa-mir-3150a-5p ; hsa-mir-3150b-5p ; hsa-mir-6736-3p ; hsa-mir-4668-5p ; hsa-mir-3065-3p ; hsa-mir-5584-5p ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-583 ; hsa-mir-2053 ; hsa-mir-4272 ; hsa-mir-218-2-3p ; hsa-mir-148a-5p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-154-5p ; hsa-mir-7855-5p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-1253 ; hsa-mir-605-3p ; hsa-mir-6813-3p ; hsa-mir-181c-3p ; hsa-mir-564 ; hsa-mir-106b-3p ; hsa-mir-4738-5p ; hsa-mir-4511 ; hsa-mir-3944-3p ; hsa-mir-3972 ; hsa-mir-3677-3p ; hsa-mir-1202 ; hsa-mir-3151-5p ; hsa-mir-185-3p ; hsa-mir-4283 ; hsa-mir-4489 ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-6739-5p ; hsa-mir-3153 ; hsa-mir-6733-5p ; hsa-mir-3194-5p ; hsa-mir-31-3p ; hsa-mir-338-3p ; hsa-mir-4446-5p ; hsa-mir-629-3p ; hsa-mir-3679-3p ; hsa-mir-6867-3p ; hsa-mir-627-3p ; hsa-mir-193b-3p ; hsa-mir-193a-3p

Nearest miRNA

hsa-mir-1285-2/Upstream/3754877; hsa-mir-10b/Downstream/1082930;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/5013, chr2-CpG: 53/Downstream/112264

Upstream sequence

tctggggaaggaccagtttttttgtttgtttGTTTTTTGTTTTTCAGTGTTCCCAAAAGATTGCAAAACTAAaacgtggtcccacttactttgtacagcg

Downstream sequence

agtttgcagctgctgcacgtgtggctcagcaccatccaaagtggtctgtgagccattcagtgaggcgagccaagtgatcatgcccttggatgtcatggta