Basic Information
VIS ID
TVIS44018913
Fusion event
HTLV-1-LOC107985902 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
79600251/79373125 (Hg38)
End
79600251/79373125 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC107985902
Nearest miRNA
hsa-mir-1285-2/Upstream/4282211; hsa-mir-10b/Downstream/276169;
Nearest TSS
ENST00000437798/Upstream/60415; ENST00000409266/Downstream/127719;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/379659, chr2-CpG: 65/Downstream/139445
Nearby gene
LOC101927987(No orient, 120591)
Upstream sequence
TGAATAAAAAGGGTGGTATAATCCTTGGCAAAATGTATAGCAATATGAAAATTTTTGTAATAAATTGTTATAATGGTTTGCGTTGTGAATTAGAATAGCA
Downstream sequence
AATACTTTGTTACAGAGTACTTACATTTTATTTTTTAGCTATCACAGCTCAAAACTAAATGTAGACGTGTGACTCTATGATACCTTCTGGCTAAAGATTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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