Basic Information
VIS ID
TVIS44018920
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
80973545/80746420 (Hg38)
End
80973545/80746420 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/879837; hsa-mir-10b/Downstream/5037180;
Nearest TSS
ENST00000437798/Upstream/127643; ENST00000448431/Downstream/123770;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/423747, chr2-CpG: 93/Downstream/447660
Nearby gene
CTNNA2(+97557) ;
Nearest cancer related gene
CTNNA2(TSG, +97557) ;
Upstream sequence
TGCATGTGAATTCTGTCACTTGCAGAGTTCCCAGACTCTGTAGACATGGCGGTGGAGTCAGGGATCATGGTCCTTTGGGTGGTTCTTTATTATTTCATGA
Downstream sequence
TTCTGTTTCTAACCACTTTCATTTTCTTATGGTGAATGCATATCTCATGAAGCTAAAACTTTCCAGCCTCCACAGGGACAGGGAAACATTCTGAATCCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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