Basic Information
VIS ID
TVIS44018922
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
81216441/80989317 (Hg38)
End
81216441/80989317 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/1122734; hsa-mir-10b/Downstream/4794283;
Nearest TSS
ENST00000437798/Upstream/119127; ENST00000448431/Downstream/477629;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/666644, chr2-CpG: 93/Downstream/204763
Nearby gene
CTNNA2(+340453) ;
Nearest cancer related gene
CTNNA2(TSG, +340453) ;
Upstream sequence
tctatgggatacagtaaaagcaacacaagaggaaagtttatagcaataagcacttacatcaaaaaagtagagaacattgaaataaccaacctaatgatac
Downstream sequence
atgttaaagaccaagaaatgcaagagcaaaccaaacccaaaattagttgaagaaaattaatgaagatcaaagcagaaataaataaaattgaaataaaaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate