Basic Information
VIS ID
TVIS44018923
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
81271651/81044527 (Hg38)
End
81271651/81044527 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/1177944; hsa-mir-10b/Downstream/4739073;
Nearest TSS
ENST00000437798/Upstream/174337; ENST00000448431/Downstream/422419;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/721854, chr2-CpG: 93/Downstream/149553
Nearby gene
CTNNA2(+395663) ;
Nearest cancer related gene
CTNNA2(TSG, +395663) ;
Upstream sequence
GCTGGAGTACTAGACAGGTTGTTGGATAAGAAATTAAAAAACAGACCAAGATGAAATAAAACCCAGTTATATGAGCTAGAAGCAGATGGAGAGAGATTCA
Downstream sequence
GATTCCACACGCTAATAAAAGAACCTTGGATTTTGACAAGAGCATTATTTTTCAGATGTTGTGAACAGAGCCGAAGAGACTGTGTTGAAAAAAAAGAAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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