Basic Information
VIS ID
TVIS44018934
Fusion event
HTLV-1-LOC107985908 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
87510894/87283771 (Hg38)
End
87510894/87283771 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2L
Target gene
LOC107985908
Nearest miRNA
hsa-mir-1285-2/Upstream/88912; hsa-mir-10b/Downstream/345984;
Nearest TSS
ENST00000437798/Upstream/30021; ENST00000421835/Downstream/54740;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/206323, chr2-CpG: 63/Downstream/57945
Nearby gene
MIR4771-2(-88912) ;
Upstream sequence
AATCactccataaagatgtacaattattatgtattaataaaaaatgaaaATAAAAAGACCGTGTAAACTGCCACGTATTCCCACTGGAGAGCTGGTGAGT
Downstream sequence
CTCTCCGTGGATCGTACCATTACCACAAGAGTCCTCTGGCCCACGCACACCCTGCTCTGCCCATCAGCAGTGCTCCCCCTCCTCTCCGCCATTGGCTTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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