Basic Information
VIS ID
TVIS44018952
Fusion event
HTLV-1-LOC105374031 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
107819808/108100961 (Hg38)
End
107819808/108100961 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105374031
Nearest miRNA
hsa-let-7g/Upstream/4576845; hsa-mir-12124/Downstream/1501867;
Nearest TSS
ENST00000440867/Upstream/9099; ENST00000607746/Downstream/24860;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/9265, chr3-CpG: 49/Downstream/121122
Nearby gene
CD47(-9873) ;
Upstream sequence
CTTTAAGAAACTGGTTTCACTGTAGTTTACAAAATGCCCTTTTTGTGTGTCCATCAAAGTACTTTGTGTCTGACATCTGTGCTAATCTCTTGTGAGTTTC
Downstream sequence
CATTTACAAGATGCCATTTTGATAAAATGCAGAAAGTGTCCATATGGTTACACAATTGTGTCTCTCTGTCTGGAGAATGAAGGAAATGAAACTGGGGGAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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