VISDB Viral Integration Site DataBase

VIS ID

TVIS44018986

Fusion event

HTLV-1-PLXNA1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

q21.3

Reference genome

Start

End

126746179/127027336 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-146a-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-186-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-30a-5p ; hsa-mir-93-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-106b-5p ; hsa-mir-30e-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-4316 ; hsa-mir-4710 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-1827 ; hsa-mir-1307-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-1233-5p ; hsa-mir-1249-5p ; hsa-mir-1287-5p ; hsa-mir-1321 ; hsa-mir-149-3p ; hsa-mir-196a-3p ; hsa-mir-3135b ; hsa-mir-3689d ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-4785 ; hsa-mir-6077 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6134 ; hsa-mir-6741-5p ; hsa-mir-6768-5p ; hsa-mir-6778-5p ; hsa-mir-6781-5p ; hsa-mir-6785-5p ; hsa-mir-6786-5p ; hsa-mir-6797-5p ; hsa-mir-6825-5p ; hsa-mir-6851-5p ; hsa-mir-6883-5p ; hsa-mir-7112-5p

Nearest miRNA

hsa-let-7g/Upstream/1236784; hsa-mir-12124/Downstream/547930;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/8820, chr3-CpG: 22/Downstream/2481

Upstream sequence

GGCGGTTCTCATGCTACAGCGCGGGGAGCCGGAGGGTGAGGGGTCAGGTGCCCGCTGAGGGCCCGGGGCTGTGCTGCTGGCCCTGTGCTGTGTGCTTGGG

Downstream sequence

TGCTGGTGAACCTCCCTGGGTGGGCAAGCCTCCTCAGGTGGGTATGTCAGTATCCATGACACACCATAGTTGTGTCCCAGAGTAATATGGGGGCCCAGCT