Basic Information
VIS ID
TVIS44018987
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
126791563/127072720 (Hg38)
End
126791563/127072720 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/1282168; hsa-mir-12124/Downstream/502546;
Nearest TSS
ENST00000440867/Upstream/40865; ENST00000624688/Downstream/120411;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/38542, chr3-CpG: 58/Downstream/62543
Nearby gene
PLXNA1(+35328) ;
Upstream sequence
gcctgtgtcgagcccttcccagcaggttcccttccccctctcatttcttcacagccctccagggggtcttgggctcagcccccatgcacactactggcac
Downstream sequence
tggaatccttgcatagccttgaaggaacccatatggagacTGTGGGGCTGGGCAAGGCTGGGAGGTGTGGGCCTGCCCTGAAGCTGGGTGAGGGTCCCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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