VISDB Viral Integration Site DataBase

VIS ID

TVIS44019058

Fusion event

HTLV-1-ABCC5 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

q27.1

Reference genome

Start

End

183691583/183973795 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-1229-3p ; hsa-mir-935 ; hsa-mir-423-5p ; hsa-mir-188-5p ; hsa-mir-129-5p ; hsa-mir-4308 ; hsa-mir-4254 ; hsa-mir-6510-5p ; hsa-mir-1304-5p ; hsa-mir-1273h-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-4771 ; hsa-mir-3166 ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-3184-5p ; hsa-mir-873-3p ; hsa-mir-499b-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-491-5p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-185-3p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-1199-3p ; hsa-mir-2467-3p ; hsa-mir-6820-5p ; hsa-mir-6087 ; hsa-mir-6805-5p ; hsa-mir-4758-3p ; hsa-mir-766-3p ; hsa-mir-610 ; hsa-mir-1224-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-4323 ; hsa-mir-634

Nearest miRNA

hsa-let-7g/Upstream/86910; hsa-mir-1224/Downstream/267610;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/88709, chr3-CpG: 86/Downstream/43557

Upstream sequence

CACTCTCGAGTAACCTTAGGTGTGGCCCCCGCTTGCTGAAATGGCTGCTGCTTTCATTTGTTCAAAGCCTTCCTGAGAGATTGAACTAAGAGTAACATGC

Downstream sequence

CAAACATTTTGATCACCTTCACAGAGTAAAACCACATGCCGACAGAATTTCCATCATTTCTCTCCCTTAAAGAGTTATTCAAAGGATGAAGGTCTTTTAG