Basic Information
VIS ID
TVIS44019060
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
GRCh37/hg19
Start
184339588/184621800 (Hg38)
End
184339588/184621800 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA3C
Nearest miRNA
hsa-let-7g/Upstream/380311; hsa-mir-1248/Downstream/631410;
Nearest TSS
ENST00000440867/Upstream/42052; ENST00000610001/Downstream/90202;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/17188, chr3-CpG: 59/Downstream/89778
Nearby gene
EPHB3(+39392) ;
Nearest cancer related gene
EPHB3(TSG, +39392) ;
Upstream sequence
tttttatttgtcaattagacctcaataaagctagaaaaaagcaatcgggaaaagagggattcttcagcaagtattgtagagacaattggctatccttgtg
Downstream sequence
gaaaaaaaccataaagttagattcgtgcttcacaccattcactgaaataaattccagatggattagagagctcaatgtgaaaaaaacaaagctataaaac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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