Basic Information
VIS ID
TVIS44019062
Fusion event
HTLV-1-LOC105374257 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.2
Reference genome
GRCh37/hg19
Start
185852305/186134516 (Hg38)
End
185852305/186134516 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
LOC105374257
Nearest miRNA
hsa-let-7g/Upstream/366612; hsa-mir-1248/Downstream/652156;
Nearest TSS
ENST00000440867/Upstream/24198; ENST00000421006/Downstream/30451;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/25421, chr3-CpG: 75/Downstream/59039
Nearby gene
DGKG(-12685) ;
Upstream sequence
TGTGCTTTTAGTTAGCTACTGCCCCAATCATGGCTGGTAAAGTCTGCATTTCTGCACTGCAATGGAGGTGTGTTAGGACCTTTAGCTTCAACCTGTGCCC
Downstream sequence
AGGGTCATCCCTAAACACTGAGGTTTAGCTGAGTTCCGTAAGTGGAAGCAGTGCTTCTCCACTGTGGGACTGAATTCTCTCCCAGCACACTGGCAATTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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