Basic Information
VIS ID
TVIS44019071
Fusion event
HTLV-1-LOC102724877 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37/hg19
Start
193789221/194071432 (Hg38)
End
193789221/194071432 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102724877
Nearest miRNA
hsa-let-7g/Upstream/4241423; hsa-mir-3137/Downstream/1063074;
Nearest TSS
ENST00000440867/Upstream/1193; ENST00000457815/Downstream/20129;
Nearest CpG islands
chr3-CpG: 87/Target, None/Upstream, None/Downstream
Nearby gene
HES1(+64710) ;
Upstream sequence
GCTGCGAGTCAAGGCAGCGCCGGGAGCTGCCGACGAGCAGGTTCCGACTTTGGCACCCGCCGCGCCGCCTTCCCGCCTTCCCCACGCCCGGCGGGGGCGG
Downstream sequence
AGGGGGACGCAGAGGGGCCCGCGCCGGCGGCTTAACCCTTGGACGTCTAGACACAACTTTGATCAGCAGTTTATTGAATCTCAGTGTGTGTCTCACCCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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