Basic Information
VIS ID
TVIS44019102
Fusion event
HTLV-1-LOC105377061 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
45356262/45314770 (Hg38)
End
45356262/45314770 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105377061
Nearest miRNA
hsa-mir-12127/Upstream/452789; hsa-let-7g/Downstream/2534785;
Nearest TSS
ENST00000440867/Upstream/88492; ENST00000430399/Downstream/73736;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/88223, chr3-CpG: 21/Downstream/73754
Nearby gene
LARS2(+73813) ;
Upstream sequence
tctgagaagactggttgaaggaagtggctttcagtctaggtcttgggggagatgaaatttcatcctgcagacatgaggacagggccagaggtaaccagca
Downstream sequence
agcaaaaagacactgttaacttttactgcataaagaattatccccggctgggtgtggtggctcacgcctgtaatcccagcactttgggaggcagaggtgg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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