VISDB Viral Integration Site DataBase

VIS ID

TVIS44019113

Fusion event

HTLV-1-ARL8B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

p26.1

Reference genome

Start

End

5175342/5133657 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-16-1-3p ; hsa-mir-4477a ; hsa-mir-4291 ; hsa-mir-5589-3p ; hsa-mir-539-5p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-4519 ; hsa-mir-4714-5p ; hsa-mir-659-3p ; hsa-mir-6516-5p ; hsa-mir-29b-2-5p ; hsa-mir-455-3p ; hsa-mir-6888-3p ; hsa-mir-934 ; hsa-mir-3618 ; hsa-mir-1251-3p ; hsa-mir-631 ; hsa-mir-3661 ; hsa-mir-9-5p ; hsa-mir-3120-5p ; hsa-mir-622 ; hsa-mir-223-3p ; hsa-mir-4697-3p ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-1243 ; hsa-mir-3654 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-1273e ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-219b-3p ; hsa-mir-7162-3p ; hsa-mir-665 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6888-5p ; hsa-mir-890 ; hsa-mir-302f

Nearest miRNA

hsa-let-7g/Downstream/116520;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/10802, chr3-CpG: 132/Downstream/53616

Upstream sequence

CCATCAGCAAACAGCAGTTACAGGGTGGGGAAGAAAGAATGGGTTTAGAAGAAAAAGGGATGATTTGAGTATAAATTGTATTACAGGCTGgggcgtggtg

Downstream sequence

gctcatgccagtaaccccagcactttgggaggctgagaagggtgtggatcctttgagctcaggagttcaaggccagcttaggcaacatagtgaaactctg