Basic Information
VIS ID
TVIS44019123
Fusion event
HTLV-1-C3orf67-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
58932911/58947185 (Hg38)
End
58932911/58947185 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA3B
Target gene
C3orf67-AS1
Nearest miRNA
hsa-let-7g/Upstream/3094591; hsa-mir-12124/Downstream/1670620;
Nearest TSS
ENST00000440867/Upstream/97959; ENST00000487624/Downstream/99126;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/360009, chr3-CpG: 57/Downstream/102495
Upstream sequence
AATTATTTACAAGTCTATCTGACAACTCCAAGGTTAGTAGTTACCTGGCTCAGTGTTTTTAAAAGGTTGCATGCTTCCTCtgggaaggaaagagagcagc
Downstream sequence
aggcctgcaaccatttactttactttactaaagggcattccagaaaaaaaagatataagaccagccaaaactccctgtaaacatgagcgaacttccctgg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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