Basic Information
VIS ID
TVIS44019124
Fusion event
HTLV-1-LOC105377110 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
59299493/59313767 (Hg38)
End
59299493/59313767 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3B
Target gene
LOC105377110
Nearest miRNA
hsa-let-7g/Upstream/3461173; hsa-mir-12124/Downstream/1304038;
Nearest TSS
ENST00000440867/Upstream/248617; ENST00000475527/Downstream/74937;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/263549, chr3-CpG: 48/Downstream/1937165
Nearby gene
C3orf67(No orient, 263778)
Upstream sequence
GAGTCCTGGCTTGACTTCATTTCAGAGTAGCAGATATTGTCCACACCAAATGGGAAATGTTTGGAACCTGGAACCTACTTCCTTCTAATCTTACTTAGGG
Downstream sequence
TTGCTTAGCTGCAGAGTAATCTGAGAGTTACCCTGACACTAGGATGGGTGGGATATGATTTGAATCAAGTCTGTTTTACCATTATTCCTGCCTTGACTGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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