Basic Information
VIS ID
TVIS44019127
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
61423048/61437374 (Hg38)
End
61423048/61437374 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA3B
Nearest miRNA
hsa-let-7g/Upstream/819504; hsa-mir-12124/Downstream/5788090;
Nearest TSS
ENST00000440867/Upstream/185915; ENST00000475527/Downstream/124195;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/185821, chr3-CpG: 248/Downstream/123280
Nearby gene
PTPRG(+124195) ;
Upstream sequence
aatgatttatattcctttgggtatatattcagtaatgggattgctggattaaatggtagttctgtttttagctctttgaggaattaccacactgctttcc
Downstream sequence
acaatggttaaactaatttacacctccaccagcattccctccagcatctgttatttttttactttttaataacagccattctgactggtgtgagatggca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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