Basic Information
VIS ID
TVIS44019131
Fusion event
HTLV-1-SYNPR-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
63420893/63435217 (Hg38)
End
63420893/63435217 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA3B
Target gene
SYNPR-AS1
Nearest miRNA
hsa-let-7g/Upstream/2817347; hsa-mir-12124/Downstream/3790247;
Nearest TSS
ENST00000440867/Upstream/83788; ENST00000467934/Downstream/7860;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/156688, chr3-CpG: 152/Downstream/428153
Upstream sequence
TAAACTTGCGCACATTCGCAAGACTGGGTAATGTGGAGATTTATaacctgggctttggaaacagacaacccaggttcaagcctttgttcaaatatttact
Downstream sequence
atccaggcagactttggcaacttactgaaccgcactaaaccttatcattttcgtttgtaaaatgatgataacaatagattctagtagatcaggttgaatg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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