Basic Information
VIS ID
TVIS44019136
Fusion event
HTLV-1-SUCLG2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
67751161/67700737 (Hg38)
End
67751161/67700737 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
SUCLG2-AS1
Nearest miRNA
hsa-let-7g/Upstream/475210; hsa-mir-12124/Downstream/1348221;
Nearest TSS
ENST00000440867/Upstream/32490; ENST00000491017/Downstream/303479;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/46155, chr3-CpG: 21/Downstream/307019
Upstream sequence
tcaaagtgctgggattaccggtatggccaccatgccaggcTTCAGTTTCTTCGAAATGAAAACAGAGTTTAAGTGAAATACAACATGAGAAATTTGAAGT
Downstream sequence
GAATTCATCTGATAAGCCAAGTAATTTACAGAAATGATCCATGAAGATAATGTGCAATGAAGAACAGATGCCAAATTACACTGGATATTTTCTGTTTTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate