Basic Information
VIS ID
TVIS44019150
Fusion event
HTLV-1-ZNF717 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
75804241/75755090 (Hg38)
End
75804241/75755090 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF717
Nearest miRNA
hsa-let-7g/Upstream/16727; hsa-mir-12124/Downstream/3752797;
Nearest TSS
ENST00000440867/Upstream/80677; ENST00000475034/Downstream/29968;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/82332, chr3-CpG: 48/Downstream/30013
Upstream sequence
tgaattcaacattgcagaaactgtgaaagcaagaagacagtgaaatggaaaattcaaaatgttgacagaaaaaaaacccaccaacctaagtttctgtacc
Downstream sequence
cactgaaaccacccttcaaaagtgaaggagaattaaggccttcctcagaaaaataaaaattcaagaaacttgttgccaggagacctgtcttgcaagaaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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