Basic Information
VIS ID
TVIS44019158
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
78340730/78291580 (Hg38)
End
78340730/78291580 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/2553217; hsa-mir-12124/Downstream/1216307;
Nearest TSS
ENST00000440867/Upstream/24574; ENST00000473938/Downstream/315709;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1193332, chr3-CpG: 49/Downstream/727333
Nearby gene
ROBO1(-305658) ;
Nearest cancer related gene
ROBO1(TSG, -305658) ;
Upstream sequence
AATTAATGCTTGAAAACACAATTTTTAAACTTTTAAATATATTATTGTAAAACGATCTCAAAGGTAAGTTAATATGTTTTAAAAAAACACAATTGTTTCC
Downstream sequence
AAAACCACTGTTTTTATTAAGAGTGATAATAATAAAATATGTCTCCATCTAGTTTAACAGTATACtaagtcctcacctaatgtcactgataggtttttgg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate