Basic Information
VIS ID
TVIS44019159
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
78590810/78541660 (Hg38)
End
78590810/78541660 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/2803297; hsa-mir-12124/Downstream/966227;
Nearest TSS
ENST00000440867/Upstream/274654; ENST00000473938/Downstream/65629;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1443412, chr3-CpG: 49/Downstream/477253
Nearby gene
ROBO1(-55578) ;
Nearest cancer related gene
ROBO1(TSG, -55578) ;
Upstream sequence
agagacatctgggaaccccagctggcagctggggccactttggtcaggcctggagacatccagcaccagtgagacctaggtggtttgtggcaaatgcccg
Downstream sequence
tgacctcctacagcctcagtttcatgaggattcaaggggatgccctgaaccccatcatggtctagcctggctcatgggggcacccatgacttcctggact
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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