Basic Information
VIS ID
TVIS44019200
Fusion event
HTLV-1-BANK1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q24
Reference genome
GRCh37/hg19
Start
102738482/101817325 (Hg38)
End
102738482/101817325 (Hg38)
Orient
-
Location type
Intronic
Target gene
BANK1
miRNAs that regulate target gene
hsa-mir-7641 ; hsa-mir-4662a-5p ; hsa-mir-590-3p ; hsa-mir-6768-3p
Nearest miRNA
hsa-mir-12113/Upstream/486911; hsa-mir-1243/Downstream/7671373;
Nearest TSS
ENST00000502981/Upstream/3499; ENST00000510950/Downstream/164538;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/26283, chr4-CpG: 100/Downstream/527145
Upstream sequence
attttatgttcatcgcagcattattcacaatagtaaatttatgaaatcaacccaaatgcccatcaatgatagactggataaagaaagtgtggtacatgta
Downstream sequence
caccatggaattctatgcagccataaaaaggaatgcgattatgtcctttgcagagaaatggatggtgctgaaggccatcatccttagcaaactaatgcat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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