Basic Information
VIS ID
TVIS44019201
Fusion event
HTLV-1-SLC39A8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q24
Reference genome
GRCh37/hg19
Start
103172338/102251181 (Hg38)
End
103172338/102251181 (Hg38)
Orient
-
Location type
UTR3
Target gene
SLC39A8
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-30c-1-3p ; hsa-mir-331-3p ; hsa-mir-1260b ; hsa-mir-488-3p
Nearest miRNA
hsa-mir-12113/Upstream/920767; hsa-mir-1243/Downstream/7237517;
Nearest TSS
ENST00000502981/Upstream/189765; ENST00000511926/Downstream/53307;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/460139, chr4-CpG: 100/Downstream/93289
Upstream sequence
acatatttatggggtacatagtgatgttatacatataatgtatgtatatgtgatgcatataatgtataggaatcagattaaggttattagcatatccatc
Downstream sequence
atctcaaatagttgtcatttctttgtgttgggaacattcatatgttccttctagctacttgaaactaaataatatattattgttagctatagccatccta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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