Basic Information
VIS ID
TVIS44019204
Fusion event
HTLV-1-TET2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q24
Reference genome
GRCh37/hg19
Start
106186637/105265480 (Hg38)
End
106186637/105265480 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
TET2-AS1
Nearest miRNA
hsa-mir-12113/Upstream/3935066; hsa-mir-1243/Downstream/4223218;
Nearest TSS
ENST00000502981/Upstream/87417; ENST00000265154/Downstream/134156;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/118669, chr4-CpG: 82/Downstream/207914
Upstream sequence
TGTCTTCCAGACATTTAGATGGATTTCCAGTAATTCATTCACAAAATCCTGCATGGTATTTTTTAGGAGATGGCATAAGTGTAATTTCTAGCTGATTGTA
Downstream sequence
TATCTGTTTTTGTTCAAGAAACAGAATAAAGCTAACTAGACCACAGCATGAACTGAACGGCCACAAAGCACACATCTATGTTAAAGAGTAGTTGGTACCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate