Basic Information
VIS ID
TVIS44019208
Fusion event
HTLV-1-RNF212 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
1099231/1105443 (Hg38)
End
1099231/1105443 (Hg38)
Orient
-
Location type
Intronic
Target gene
RNF212
Nearest miRNA
hsa-mir-571/Upstream/755191; hsa-mir-12113/Downstream/880941;
Nearest TSS
ENST00000502981/Upstream/5583; ENST00000504969/Downstream/8072;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/8943, chr4-CpG: 15/Downstream/7138
Upstream sequence
CTGGCTTCAGTCTGCTCTGCTCCCTGGCCATCCACCACCCAACCAATACGGTGGTGCCCTATTCTGTGCGTTCAATCGTAATGGAGCATTataatgacaa
Downstream sequence
acaaatcaatatataaagatatctcaggtggtgacacacactgcgaagcagaataatccaggtcaaggaacacagCGTCAGAGGGTCACTTTTACATGGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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