Basic Information
VIS ID
TVIS44019217
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
GRCh37/hg19
Start
120012392/119091237 (Hg38)
End
120012392/119091237 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/4434383; hsa-mir-1305/Downstream/6416022;
Nearest TSS
ENST00000502981/Upstream/67766; ENST00000307128/Downstream/44547;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/254581, chr4-CpG: 67/Downstream/121172
Nearby gene
SYNPO2(+29990) ;
Nearest cancer related gene
SYNPO2(TSG, +29990) ;
Upstream sequence
tttttctagattttctagtgtatatgcatagaggtgttcataatatcctctgatggttgtttgtattcctgtggggtcagtggtaatatcccctttgtca
Downstream sequence
tttctaattgtgtttatttgaatcttctctctttttttccttattagcctaactagtggtctatcttactaatttttaaaaaataaacagcttctagatg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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