VISDB Viral Integration Site DataBase

VIS ID

TVIS44019218

Fusion event

HTLV-1-USP53 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

q26

Reference genome

Start

End

120213569/119292414 (Hg38)

Orient

-

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-30b-5p ; hsa-mir-16-5p ; hsa-mir-186-3p ; hsa-mir-323a-5p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-876-3p ; hsa-mir-374b-3p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-4456 ; hsa-mir-548ak ; hsa-mir-4524a-5p ; hsa-mir-548am-5p ; hsa-mir-3973 ; hsa-mir-4690-3p ; hsa-mir-548ap-5p ; hsa-mir-4524b-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-5685 ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-545-3p ; hsa-mir-3120-3p ; hsa-mir-6504-3p ; hsa-mir-6792-5p ; hsa-mir-6806-5p ; hsa-mir-646 ; hsa-mir-6838-5p ; hsa-mir-503-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-6757-3p ; hsa-mir-15a-5p ; hsa-mir-497-3p ; hsa-mir-141-3p ; hsa-mir-200a-3p

Nearest miRNA

hsa-mir-12113/Upstream/4635560; hsa-mir-1305/Downstream/6214845;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/79280, chr4-CpG: 40/Downstream/8057

Upstream sequence

TTGTTTTTATTTTCATATTTCAGATCACATGTACATGAAGACAATGGAAAGTTATTTCCTTCATCCAGTCTACAAATACCCAAGGACCATAATGCAAGAG

Downstream sequence

AACATATCCACCAGTCAGATGAACAGAAACTTGAAAAACCGAATGAATGCAAATTTTCTGAGTGGCTTAATATAGAAAATTCTGAGAGAACAGGTTTGCC