VISDB Viral Integration Site DataBase

VIS ID

TVIS44019219

Fusion event

HTLV-1-TNIP3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

q27

Reference genome

Start

End

122144745/121223590 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-142-3p ; hsa-mir-4261 ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-4496 ; hsa-mir-5580-3p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-4325 ; hsa-mir-551b-5p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-4666a-3p ; hsa-mir-338-5p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-1295b-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-122-5p ; hsa-mir-129-5p ; hsa-mir-323a-5p ; hsa-mir-3650 ; hsa-mir-3911 ; hsa-mir-504-3p ; hsa-mir-6127 ; hsa-mir-7847-3p ; hsa-mir-876-3p

Nearest miRNA

hsa-mir-12113/Upstream/6566736; hsa-mir-1305/Downstream/4283669;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/150619, chr4-CpG: 67/Downstream/156822

Upstream sequence

ATATTCATGTCCTATAAGAAAATCACTTTTGCTACTTGCTTTCCAGTGAGTTTTGAATATCAAACAAGATTTAAATTCCACCACATTTATTTAGACCTTA

Downstream sequence

CAAGGCTCCACAGAAACTAGAAAAGGTAAAAATGCCTCATTATCACACGTGCATTTCATCATAGCTTTATGAGATTCAGAGCATGAAGAGCAGAAGCCAG