VISDB Viral Integration Site DataBase

VIS ID

TVIS44019240

Fusion event

HTLV-1-OTUD4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

q31.21

Reference genome

Start

End

146085386/145164234 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-30b-5p ; hsa-mir-183-5p ; hsa-mir-101-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-18a-3p ; hsa-mir-6885-3p ; hsa-mir-3163 ; hsa-mir-4255 ; hsa-mir-130b-5p ; hsa-mir-5571-5p ; hsa-mir-2681-5p ; hsa-mir-4753-3p ; hsa-mir-6809-3p ; hsa-mir-6875-3p ; hsa-mir-6516-5p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-219b-3p ; hsa-mir-6513-3p ; hsa-mir-219a-2-3p ; hsa-mir-455-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-4714-3p ; hsa-mir-4272 ; hsa-mir-4760-3p ; hsa-mir-498 ; hsa-mir-4778-3p ; hsa-mir-4282 ; hsa-mir-3591-5p ; hsa-mir-1256 ; hsa-mir-4796-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-142-3p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-106a-5p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-5682 ; hsa-mir-767-5p ; hsa-mir-3662 ; hsa-mir-6871-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-29a-3p ; hsa-mir-6807-5p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p ; hsa-mir-19a-3p ; hsa-mir-219a-1-3p ; hsa-mir-3125 ; hsa-mir-31-5p ; hsa-mir-3646 ; hsa-mir-3675-5p ; hsa-mir-3916 ; hsa-mir-4466 ; hsa-mir-4699-5p ; hsa-mir-4706 ; hsa-mir-4709-3p ; hsa-mir-4723-5p ; hsa-mir-4749-5p ; hsa-mir-486-3p ; hsa-mir-5698 ; hsa-mir-570-3p ; hsa-mir-675-5p ; hsa-mir-6795-5p ; hsa-mir-6825-5p ; hsa-mir-6859-5p ; hsa-mir-6870-5p ; hsa-mir-6887-5p ; hsa-mir-7106-5p ; hsa-mir-7111-5p ; hsa-mir-744-5p ; hsa-mir-766-5p

Nearest miRNA

hsa-mir-12113/Upstream/1820699; hsa-mir-1305/Downstream/1244349;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/65560, chr4-CpG: 143/Downstream/15368

Upstream sequence

CACTTTGAAAAATTCTTACCTTTTCAGGAAAATTATTTTCTGTTACTTGTGAAGGAGAAACATTTGGTTCCCGATAAATTATAAAATCTTTCCTGAAAAT

Downstream sequence

AACAATTAGAAATTATTTATAATGGACTATACTTCATGAATTTGAATTTAAtcattcattcattcatcaagggcctaatacgtgccaggcactgtcccaa