Basic Information
VIS ID
TVIS44019268
Fusion event
HTLV-1-FSTL5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
162786509/161865357 (Hg38)
End
162786509/161865357 (Hg38)
Orient
-
Location type
Intronic
Target gene
FSTL5
Nearest miRNA
hsa-mir-12113/Upstream/2736463; hsa-mir-1305/Downstream/1228217;
Nearest TSS
ENST00000502981/Upstream/200453; ENST00000513093/Downstream/157376;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2761374, chr4-CpG: 71/Downstream/1300952
Upstream sequence
GAGTTTTAAGTACTTCTACAGAGAAATAATTGTAAAAACTATGGGGAAAAGTCCACATATCCCTTATGCAGTTTAAAATTAATTGTGCAAAGATCATTAT
Downstream sequence
TCAATTTATAAGTCAGTTGAAGAATAATTTGAAGCAAATCATAGGTTTAAGAATATCACCATGAAGTACATATAAAAGTAAATATAAACATACAATCAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate