Basic Information
VIS ID
TVIS44019269
Fusion event
HTLV-1-FSTL5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
162834471/161913319 (Hg38)
End
162834471/161913319 (Hg38)
Orient
+
Location type
Intronic
Target gene
FSTL5
Nearest miRNA
hsa-mir-12113/Upstream/2784425; hsa-mir-1305/Downstream/1180255;
Nearest TSS
ENST00000502981/Upstream/248415; ENST00000513093/Downstream/109414;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2809336, chr4-CpG: 71/Downstream/1252990
Upstream sequence
taatctccaagaccatggggaaaatgtctccaggccatgccagagaccttcatggcagccgcttccatcacaggcccggaggcccaggaagaaaaagtgg
Downstream sequence
tttggtaggctgggtccagggtcactgtgttgtgtgcagcctagggacttggtgccctgcgtcccagtcactccagccatggctgaaaggggccaagata
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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