Basic Information
VIS ID
TVIS44019293
Fusion event
HTLV-1-LOC105377541 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q34.1
Reference genome
GRCh37/hg19
Start
174256955/173335804 (Hg38)
End
174256955/173335804 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377541
Nearest miRNA
hsa-mir-12113/Upstream/67571; hsa-mir-1305/Downstream/1087991;
Nearest TSS
ENST00000502981/Upstream/679; ENST00000504618/Downstream/34011;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/417, chr4-CpG: 176/Downstream/33995
Nearby gene
HMGB2(-1360) ;
Upstream sequence
TTTGAGGGATTCCCCCCATTATTGGAATATAGGTTGCGTGACTGTTTCAAGAAATTTAAATATTTTGTCTTAATTTTTCAGTAAGTTCGTTGGCACATGT
Downstream sequence
TAAGACTATGCTCTTTGGTTTGTATATGGTTGTCATAATAGTATTTGAAAACCAGCAGTTGTTTATCTAGGTTTACTAATAAAAAAGATCTTAAAAAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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