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TVIS44019303
Basic Information
VIS ID
TVIS44019303
Fusion event
HTLV-1-STOX2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
184743761/183822608 (Hg38)
End
184743761/183822608 (Hg38)
Orient
+
Location type
Intronic
Target gene
STOX2
miRNAs that regulate target gene
hsa-mir-192-5p
;
hsa-mir-186-5p
;
hsa-mir-222-3p
;
hsa-mir-3611
;
hsa-mir-599
;
hsa-mir-3161
;
hsa-mir-4709-3p
;
hsa-mir-383-3p
;
hsa-mir-5590-3p
;
hsa-mir-142-5p
;
hsa-mir-6505-5p
;
hsa-mir-548aw
;
hsa-mir-190a-3p
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-1273f
;
hsa-mir-4708-5p
;
hsa-mir-4324
;
hsa-mir-331-3p
;
hsa-mir-6810-3p
;
hsa-mir-6801-3p
;
hsa-mir-5011-5p
;
hsa-mir-410-3p
;
hsa-mir-576-3p
;
hsa-mir-1277-5p
;
hsa-mir-125a-5p
;
hsa-mir-125b-5p
;
hsa-mir-4319
;
hsa-mir-143-3p
;
hsa-mir-4770
;
hsa-mir-6088
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-574-5p
;
hsa-mir-4669
;
hsa-mir-3657
;
hsa-mir-6867-5p
;
hsa-mir-127-5p
;
hsa-mir-7843-3p
Nearest miRNA
hsa-mir-12113/Upstream/1653230; hsa-mir-3945/Downstream/1028405;
Nearest TSS
ENST00000502981/Upstream/24916;
ENST00000511250/Downstream/30823;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/24007
,
chr4-CpG: 191/Downstream/82492
Upstream sequence
gagacagtgacagatcatcaggcattagattctcataaggagcacacaccccagatccctcacatgcgcagttcacaaaagggttcacgctcccatgacc
Downstream sequence
atctaacgctgccgcggatctgacaggaggcgcagctcaggtggccatctgagcgatggggagcagctgcaaatgcagatgaagcttccctggctcgcct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#2
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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