Basic Information
VIS ID
TVIS44019308
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
185998509/185077355 (Hg38)
End
185998509/185077355 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02436 ; LOC105377588
Nearest miRNA
hsa-mir-12113/Upstream/138915;
Nearest TSS
ENST00000502981/Upstream/14898; ENST00000491736/Downstream/65886;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/55762, chr4-CpG: 132/Downstream/50032
Nearby gene
HELT(+56551) ;
Upstream sequence
TGTCATTAACATTTATCTACCTGAAATTGAGGGGAATAGGCCAGGCTCATGTCACCTCTATGGTTAGTGCCCCGACCTCTCTCTTTCCACCCTGCCCCTT
Downstream sequence
TCCTTTGGCACTGACACTTGGACCTCAGTGCCTCTACCCTGCTGCCTTCTGGAAGTTCAGGACACTCCCTTCATAACAACTTGCTTGTACTTCTCTTTGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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