Basic Information
VIS ID
TVIS44019355
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p12
Reference genome
GRCh37/hg19
Start
45427287/45425270 (Hg38)
End
45427287/45425270 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/4923151; hsa-mir-1243/Downstream/2227399;
Nearest TSS
ENST00000502981/Upstream/415730; ENST00000502455/Downstream/698811;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/698568, chr4-CpG: 65/Downstream/964616
Nearby gene
GABRG1(-610500) ;
Upstream sequence
GTGAGATGTGTTTGGATTTTAGTAGTATAGAAATATAAAAACAATGACCCTTTCATATGCCCTCTCTATAAGATTATCATCATTGGGTAAGTTCACACTT
Downstream sequence
ATGCCTAGTTGTGCTAGTGGCACATGTGACTTAAAAAGCAGATGCCACTGATGACTTCATCTCATCAGCTTCTTTTCAGTGATTAATTACAGCATCTGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate