Basic Information
VIS ID
TVIS44019410
Fusion event
HTLV-1-LINC01088 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
GRCh37/hg19
Start
80050828/79129674 (Hg38)
End
80050828/79129674 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01088
Nearest miRNA
hsa-mir-12113/Upstream/2554048; hsa-mir-1243/Downstream/3623663;
Nearest TSS
ENST00000502981/Upstream/44435; ENST00000511895/Downstream/66160;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/190083, chr4-CpG: 39/Downstream/835016
Upstream sequence
cagccaaagcacttcatagggcagtgacagtgggatccatcctcactcacatgtgccagtggcagtggcagtgcagaaggtttcatgtttgtcagctgaa
Downstream sequence
gcagggttctagcaggtgcaggggtgttggcctccctgtgggtgttcacagcagcagtggtgacagtatggcacaagggatcaggggttctcactggtga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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