Basic Information
VIS ID
TVIS44019411
Fusion event
HTLV-1-LINC02469 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
GRCh37/hg19
Start
80590059/79668905 (Hg38)
End
80590059/79668905 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02469
Nearest miRNA
hsa-mir-12113/Upstream/3093279; hsa-mir-1243/Downstream/3084432;
Nearest TSS
ENST00000502981/Upstream/5144; ENST00000504263/Downstream/158566;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/729314, chr4-CpG: 39/Downstream/295785
Nearby gene
LINC00989(No orient, 92445)
Upstream sequence
gtggctagacccagaagatcaaaaacaatcactacagtttggctctcaggaagccccattcctaggagaagtgggagaacaccacaccaagggagtaccc
Downstream sequence
catgggacaaaagaaactgaacagcagcccttgaatcccagatcttccctctgacatagtctacccaaatgagaaggaaccagaaaaacatttctggtaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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