Basic Information
VIS ID
TVIS44019412
Fusion event
HTLV-1-CFAP299 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
GRCh37/hg19
Start
81506891/80585737 (Hg38)
End
81506891/80585737 (Hg38)
Orient
-
Location type
Intronic
Target gene
CFAP299
Nearest miRNA
hsa-mir-12113/Upstream/4010111; hsa-mir-1243/Downstream/2167600;
Nearest TSS
ENST00000502981/Upstream/249956; ENST00000621014/Downstream/284312;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/198939, chr4-CpG: 88/Downstream/445050
Upstream sequence
TGAATGTCCTTAAAATAATGTATACAAATGGTTAATGTGATCAGACATGCAACTTAAGAGTACACTGGCAGCAGTATATGGGGATAAGTGTGTCTCCATA
Downstream sequence
GAGATAGGGAATGATATATAAGACAGGGAGGTCAACTGAGAGGCCATTGTAACAGTTCAGGCAATACATAATAGATGCATAATAGAAGCCTGGGATAAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate