VISDB Viral Integration Site DataBase

VIS ID

TVIS44019432

Fusion event

HTLV-1-PDLIM5 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

q22.3

Reference genome

Start

End

95492095/94570944 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-16-5p ; hsa-mir-17-5p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-133a-3p ; hsa-mir-3149 ; hsa-mir-4758-3p ; hsa-mir-6872-3p ; hsa-mir-4267 ; hsa-mir-8057 ; hsa-mir-4284 ; hsa-mir-24-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-6890-3p ; hsa-mir-6800-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-607 ; hsa-mir-6836-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-205-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-1909-3p ; hsa-mir-193b-5p ; hsa-mir-3150b-3p ; hsa-mir-3170 ; hsa-mir-4453 ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4538 ; hsa-mir-4689 ; hsa-mir-4710 ; hsa-mir-4784 ; hsa-mir-5572 ; hsa-mir-6132 ; hsa-mir-6722-3p ; hsa-mir-6737-5p ; hsa-mir-6812-5p ; hsa-mir-6819-5p ; hsa-mir-6836-5p ; hsa-mir-6855-5p ; hsa-mir-6858-5p ; hsa-mir-98-5p

Nearest miRNA

hsa-mir-12113/Upstream/7270361; hsa-mir-1243/Downstream/4426443;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/118560, chr4-CpG: 137/Downstream/186703

Upstream sequence

AAACACCCTCCTTTTTTTCTGTGTGATTGTTTACGAGTTAAGTATATTAGATGCTTGAGGGAGTCACCAAGACATAATGAGTAATGTGCATAATCTTTAT

Downstream sequence

CATTCTAGTTCTATTGTCTAGTTCCTCATTCTTAAACACTAATGCGAACATTCAGAACCTTATTAACTAAAAACCATGTTATTTTATAAAGCAGTTTTAG