Basic Information
VIS ID
TVIS44019438
Fusion event
HTLV-1-DAPP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q23
Reference genome
GRCh37/hg19
Start
100755463/99834306 (Hg38)
End
100755463/99834306 (Hg38)
Orient
+
Location type
Intronic
Target gene
DAPP1
Nearest miRNA
hsa-mir-12113/Upstream/836846; hsa-mir-1243/Downstream/1406489;
Nearest TSS
ENST00000502981/Upstream/17456; ENST00000514301/Downstream/30566;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/180809, chr4-CpG: 68/Downstream/111865
Upstream sequence
tGCTCGTATGTTTGTAGAATCAGGAGTGGAGGTACACATCCAATGCCTCTAAGTGTGTAGACTATCTCTTAAGAGGAAGCACAGGAAAATGGTTACCAAG
Downstream sequence
GTGTCCTCTAGGAAAGGAACAGGGAGCCTGAGGGCCCAGGGTGAAGAAAACATGTTTTGCTATGTCTCCTTTTGGACAATTTGAATTTTTTTTTTTTTAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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