Basic Information
VIS ID
TVIS44019443
Fusion event
HTLV-1-LOC105379107 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
102973105/103637404 (Hg38)
End
102973105/103637404 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
LOC105379107
Nearest miRNA
hsa-mir-10397/Upstream/2820839; hsa-mir-103a-1/Downstream/6876425;
Nearest TSS
ENST00000502646/Upstream/74611; ENST00000514769/Downstream/442507;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/377555, chr5-CpG: 253/Downstream/4032025
Nearby gene
NUDT12(-74603) ;
Upstream sequence
TTTTCTGCCATATGAGGCCAATTATTTCAtcctttcttttcttatctttttttttcttttattctctGGTTTTTACTTCAGAAACAGCCCAACTTCATTG
Downstream sequence
GTTTGGGGTTCATTAATCAGACTAGTTATTCACCTGACACAGACCCTTATTCTATTATTCCAGATAGGCACAAAGCTATTAATATATCTTTTTGTTTTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate