Basic Information
VIS ID
TVIS44019476
Fusion event
HTLV-1-TRPC7-AS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
135647065/136311377 (Hg38)
End
135647065/136311377 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
TRPC7-AS2
Nearest miRNA
hsa-mir-10397/Upstream/508302; hsa-mir-103a-1/Downstream/1336195;
Nearest TSS
ENST00000502646/Upstream/7620; ENST00000511165/Downstream/53877;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/118087, chr5-CpG: 56/Downstream/45332
Upstream sequence
AAGCCCAGAGATGAGGAAGCAATCTAGAGGAGAGAGAGGGATGGATGAGAGTGTGTCTTCTGTTAGACAAGTTGAGTAGAGTGCCAACAACTCTGTCTGG
Downstream sequence
GTCTCTGTTCCCTGTCACTAAGCACTGACCACATGGCAGACACTGGGGTCCCTTCATAACTGCAGCCTGAGTCCAGCTGGGCCTAAACTGGGATTCAGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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