Basic Information
VIS ID
TVIS44019490
Fusion event
HTLV-1-CTB-99A3.1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
GRCh37/hg19
Start
145953455/146573892 (Hg38)
End
145953455/146573892 (Hg38)
Orient
+
Location type
Intronic
Target gene
CTB-99A3.1
Nearest miRNA
hsa-mir-10397/Upstream/2893921; hsa-mir-103a-1/Downstream/2488421;
Nearest TSS
ENST00000502646/Upstream/10666; ENST00000503975/Downstream/26484;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/126025, chr5-CpG: 97/Downstream/303891
Nearby gene
PPP2R2B(-15612) ;
Upstream sequence
AAAGCTCATTAATATTACTGGAGATCAACTTTTAGAATTCTTGAACTAAAGcagggatagagaagtttcatttcatatgctgactttgattgaacagtaa
Downstream sequence
agattgcttagagtcctgtttttggggaaaaacatgtctgaggccctctctgggctcaatgagtgagaattctgtgattgattgatttctgtgatgggtg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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